The DOE Toolkit is an add-on for Mathematica® that enables you to generate all the classical experimental designs as well as more modern designs within your Mathematica® notebook.
 
The functions that the DOE Toolkit provides enable you to create the following types of experimental designs:
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Full Factorial
Fractional Factorial
Box-Behnken
Central Composite
Mixture
Orthogonal
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Each DOE Toolkit function creates the design you specify in the form of a Mathematica Dataset object.  Thus, you can leverage all the power of  Mathematica's Dataset technology to modify and analyze your designs.
 
In addition to its design generators, the DOE Toolkit provides the following tools:
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The Augment tool makes it easy to add central points, axial point groups, replicates, and blocking to your design.
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The Optimizer allows you to find an optimal subset of runs based on a previously generated design.
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Once you have generated your design and recorded your experimental results, the Desirability Manipulator allows you to visually explore the consequences of changing factor settings in your model.